(4-Bromophenyl)boronic acid → HCID 11152632, compound

HRID 899215Notes

Reaction equation

HRID 899215 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[N:10]([CH3:11])[C:9](=[O:12])[O:8][C:7]([CH3:14])([CH3:13])[C:6]=2[CH:15]=1.[Br:16][C:17]1[CH:22]=[CH:21][C:20](B(O)O)=[CH:19][CH:18]=1>>[Br:16][C:17]1[CH:22]=[CH:21][C:20]([NH:1][C:2]2[CH:3]=[CH:4][C:5]3[N:10]([CH3:11])[C:9](=[O:12])[O:8][C:7]([CH3:13])([CH3:14])[C:6]=3[CH:15]=2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 79599(4-Bromophenyl)boronic acidHCID 69215309HCID 69215309, compound

Product 1

HCID 11152632HCID 11152632, compound

Procedure

Prepared from 6-amino-1,4,4-trimethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one and 4-bromophenyl boronic acid according to the coupling procedure described in example 1. MS (ESI) m/z 361/363 ([M+H]+); MS (ESI) m/z 359/361 ([M−H]−); Anal. calcd for C17H17BrN2O2: C, 56.52; H, 4.74; N, 7.75. Found: C, 56.98; H, 4.34; N, 7.30.

Sources & evidence

ORD record
ord-cbd92a15efc242d1921de9e25bb2109a
Source dataset
uspto-grants-2008_04
Patent number
US07354915B2

Reaction notes

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