3-(5-Fluoro-2-hydroxyphenyl)-1-pentylindolin-2-one → 3-(5-bromo-2-hydroxyphenyl)-3-(hydroxymethyl)-1-pentyl-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:24][c:25]1[cH:26][cH:27][c:28]([OH:46])[c:29]([CH:31]2[C:32](=[O:45])[N:33]([CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])[c:34]3[cH:35][cH:36][cH:37][cH:38][c:39]32)[cH:30]1.[F:1][c:2]1[cH:3][cH:4][c:5]([OH:6])[c:7]([CH:8]2[C:9](=[O:22])[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[c:11]3[c:10]2[cH:15][cH:14][cH:13][cH:12]3)[cH:23]1>>[CH2:9]([OH:22])[C:31]1([c:29]2[c:28]([OH:46])[cH:27][cH:26][c:25]([Br:24])[cH:30]2)[C:32](=[O:45])[N:33]([CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]21Participants
3
Sources & evidence
- ORD record
- ord-f210708c4dc146ad838d1d4d76eed49f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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