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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 899507Generated: October 29, 2026

2-Chloro-4-Phenylphenol → 3-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acid

https://huagongshe.com/reaction/899507

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-PhenylphenolHCID 7074—
ReactantMethyl 3-(bromomethyl)benzoateHCID 517981—
Product3-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acidHCID 11336687—

Reaction Steps

3-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 2-chloro-4-phenylphenol (available from TCI America, Portland, Oreg.) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd., Morcambe, Lancashire, UK). Yield: 76 mg. Mass spectrum MH+=339.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07355049B2
Source datasetuspto-grants-2008_04
ORD IDord-9304112f7401485b8d47c3144da99d22
Source noteuspto-grants-2008_04