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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 899512Generated: October 28, 2026

Methyl 3-(bromomethyl)benzoate → 3-(2'-Nitro-biphenyl-4-yloxymethyl)-benzoic acid

https://huagongshe.com/reaction/899512

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(bromomethyl)benzoateHCID 517981—
Reactant4-Hydroxy-2'-nitrobiphenylHCID 15541112—
Product3-(2'-Nitro-biphenyl-4-yloxymethyl)-benzoic acidHCID 11187166—

Reaction Steps

3-(2′-Nitro-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 4-hydroxy-2′-nitrobiphenyl (available from TCI America, Portland, Oreg.) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd., Morcambe, Lancashire, UK). Yield: 82 mg. Mass spectrum (ES) MH+=350.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07355049B2
Source datasetuspto-grants-2008_04
ORD IDord-f16cf190826746c6995b854f7fad57b6
Source noteuspto-grants-2008_04