Methyl 5-(chloromethyl)-2-furoate → HCID 11245749, compound

HRID 899520Notes

Reaction equation

HRID 899520 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.C[O:16][C:17]([C:19]1[O:20][C:21]([CH2:24]Cl)=[CH:22][CH:23]=1)=[O:18]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH2:24][C:21]3[O:20][C:19]([C:17]([OH:18])=[O:16])=[CH:23][CH:22]=3)=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 75065Methyl 5-(chloromethyl)-2-furoateHCID 950934-Bromo-4'-hydroxybiphenyl

Product 1

HCID 11245749HCID 11245749, compound

Procedure

5-(4′-Bromo-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid was prepared using general procedure A from 4-bromo-4′-hydroxybiphenyl (available from TCI America, Portland, Oreg.) and 5-chloromethylfuran-2-carboxylic acid methyl ester (available from Aldrich, Milwaukee, Wis., or from Maybridge plc, Tintagel, UK). Yield: 86 mg. Mass spectrum (ES) MH+=373.

Sources & evidence

ORD record
ord-6848135f966e42478f1434c41c8d5ab3
Source dataset
uspto-grants-2008_04
Patent number
US07355049B2

Reaction notes

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