HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-4'-hydroxybiphenyl → 2-(4'-Bromo-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-4'-hydroxybiphenyl | HCID 95093 | — |
| Reactant | Ethyl 2-(bromomethyl)-1,3-thiazole-4-carboxylate | HCID 11043146 | — |
| Product | 2-(4'-Bromo-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid | HCID 11257785 | — |
Reaction Steps
2-(4′-Bromo-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid was prepared using general procedure B from 4-bromo-4′-hydroxybiphenyl (available from TCI America, Portland, Oreg.) and 2-bromomethyl-thiazole-4-carboxylic acid ethyl ester (Intermediate 3). Yield: 82 mg. Mass spectrum (ES) MH+=390.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07355049B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-f575fb4a705b4ac49b053caf62e412d1 |
| Source note | uspto-grants-2008_04 |