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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 90038Generated: October 26, 2026

Hydrochloric Acid → 1-[3,5-Bis(trifluoromethyl)phenyl]pyrrolidin-3-ol

https://huagongshe.com/reaction/90038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantPalladiumHCID 23938—
Reactant1-Bromo-3,5-bis(trifluoromethyl)benzeneHCID 67602—
ReactantDibenzylidene acetoneHCID 95417—
Reactant4-HydroxypyrrolidineHCID 98210—
ReactantBinap, (A+-)-HCID 634876—
Reactant2-Methylpropan-2-olateHCID 4574913—
Product1-[3,5-Bis(trifluoromethyl)phenyl]pyrrolidin-3-olHCID 75245196—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-15507424d2ee400f93e20eed7cddb4e4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)