Propionic Acid → HCID 86611142, compound

Participants

Reaction Steps

2,6-dichloro-4-nitroaniline (6.2 parts) was set stirring at 5° C. with a mixture of acetic acid and propionic acid, 86:14 (40 parts). Nitrosyl sulphuric acid 40% (11.4 parts) was added below 5° C. and the mixture was stirred for 30 minutes. The diazo solution was added gradually to a stirred coupling mixture of N-ethyl, N-2(cyanomethoxycarbonylethyl)-aniline (8.3 parts), methanol (50 parts), water (300 parts) and sulphamic acid (1 part). After one hour the product was isolated by filtration, washed with cold water and dried to yield, 4-(2,6-dichloro-4-nitrophenylazo)-N-ethyl-N-(2-cyanomethoxycarbonylethyl)aniline (9.5 parts) λmax=432 nm (acetone).

Provenance & Evidence