Phenyl isocyanate → HCID 21026387, compound

HRID 900410Notes

Reaction equation

HRID 900410 reaction equation
[C:1]1(N=C=O)[CH:6]=[CH:5][CH:4]=CC=1.[CH2:10]([NH:12][C:13](=[O:31])[O:14][CH:15]1[CH2:20][C:19]([CH3:22])([CH3:21])[N:18]([O:23][C:24](=[O:28])[NH:25][CH2:26][CH3:27])[C:17]([CH3:30])([CH3:29])[CH2:16]1)[CH3:11]>>[C:10]1([NH:12][C:13](=[O:31])[O:14][CH:15]2[CH2:20][C:19]([CH3:22])([CH3:21])[N:18]([O:23][C:24](=[O:28])[NH:25][C:26]3[CH:4]=[CH:5][CH:6]=[CH:1][CH:27]=3)[C:17]([CH3:29])([CH3:30])[CH2:16]2)[CH:1]=[CH:6][CH:5]=[CH:4][CH:11]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 21026383HCID 21026383, compound

Product 1

HCID 21026387HCID 21026387, compoundYield 64%

Procedure

The compound 118 is prepared using phenyl isocyanate in a procedure similar to that for preparing the compound 117, and is obtained in a 64% yield as colourless crystals; melting point: 188-190° C.

Workup

  1. customis obtained in a 64% yield as colourless crystals

Sources & evidence

ORD record
ord-77e0090cb65a44d1b2bb5ed3f39e27dd
Source dataset
uspto-grants-2008_04
Patent number
US07358365B2

Reaction notes

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