Trimethylsilyl isocyanate → HCID 17930948, compound

HRID 900417Notes

Reaction equation

[NH2:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[CH:8]=2)[S:4][C:3]=1[C:14]([NH2:16])=[O:15].C[Si]([N:21]=[C:22]=[O:23])(C)C>>[NH2:21][C:22]([NH:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[CH:8]=2)[S:4][C:3]=1[C:14]([NH2:16])=[O:15])=[O:23]

Participants

Reactant 2

HCID 70696Trimethylsilyl isocyanate

HCID 9942993HCID 9942993, compound

Product 1

HCID 17930948HCID 17930948, compound

Procedure

Prepared by the method of Example 1 from 3-amino-5-(3-chlorophenyl)-2-thiophenecarboxamide and trimethylsilylisocyanate.

Sources & evidence

ORD record: ord-998fa83204814e80ae7e5e29338aedab
Source dataset: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07358376B2

Reaction notes

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