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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 900429Generated: October 26, 2026

1-(2-Chloroethyl)pyrrolidine → 3-[(Aminocarbonyl)amino]-5-{3-[2-(1-pyrrolidinyl)ethoxy]phenyl}-2-thiophenecarboxamide

https://huagongshe.com/reaction/900429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)pyrrolidineHCID 81669—
Reactant3-[(Aminocarbonyl)amino]-5-(3-hydroxyphenyl)-2-thiophenecarboxamideHCID 9965424—
Product3-[(Aminocarbonyl)amino]-5-{3-[2-(1-pyrrolidinyl)ethoxy]phenyl}-2-thiophenecarboxamideHCID 10156267—

Reaction Steps

Prepared by the method of Example 9(b) using the product of Example 6 and N-(2-chloroethyl)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07358376B2
Source datasetuspto-grants-2008_04
ORD IDord-9a2aebb170ef4f3bbc87ea9b565fb513
Source noteuspto-grants-2008_04