Boron tribromide → HCID 9879115, compound

HRID 900436Notes

Reaction equation

HRID 900436 reaction equation
[NH2:1][C:2]([NH:4][C:5]1[S:6][C:7]([C:14]2[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=2)=[C:8]([CH3:13])[C:9]=1[C:10]([NH2:12])=[O:11])=[O:3].B(Br)(Br)Br>>[NH2:1][C:2]([NH:4][C:5]1[S:6][C:7]([C:14]2[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=2)=[C:8]([CH3:13])[C:9]=1[C:10]([NH2:12])=[O:11])=[O:3]

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 9857669HCID 9857669, compound

Product 1

HCID 9879115HCID 9879115, compound

Procedure

Prepared by demethylating 2-[(aminocarbonyl)amino]-4-methyl-5-(4-methoxyphenyl)-3-thiophenecarboxamide using boron tribromide as in Example 9(a).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c2c7241c6ffd41478fabecc23c7255fd
Source dataset
uspto-grants-2008_04
Patent number
US07358376B2

Reaction notes

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