Acetic Anhydride → HCID 131726830, compound

Participants

Reaction Steps

20.0 g of 4-Hydroxy-3,5-dimethyl phenyl dimethyl sulphonium nonaflate was taken in a round bottom flask, 50 ml acetone and 5.73 g of potassium carbonate were added and then 4.23 g of acetic anhydride was added dropwise at room temperature. The resulting mixture was stirred for 4 hours. The solution was then extracted with chloroform, washed with water, dried over sodium sulphate and filtered. The solution was concentrated and drowned into ether; a precipitate was formed, filtered and dried in the vacuum dryer at less than 40° C., yielding 4-acetoxy-3,5-dimethyl phenyl dimethyl sulphonium nonaflate, 15.0 g (70%). The solid product gave the following analytical results: 1H NMR (DMSO-d6), 2.35 (s, 6H, 2CH3); 2.45 (s, 3h, CH3); 3.5 (s, 6H, 2CH3); 7.80 (s, 2H, aromatic), mp 168° C.

Provenance & Evidence