2(3H)-Benzoxazolone → HCID 10162370, compound

HRID 900754Notes

Reaction equation

HRID 900754 reaction equation
ClC1N=C(C)N([CH2:8][C:9]2[S:24][C:12]3[N:13]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:14](=[O:19])[N:15]([CH3:18])[C:16](=[O:17])[C:11]=3[C:10]=2[C:25]([N:27]([O:29][CH3:30])[CH3:28])=[O:26])C=1Cl.[O:32]1[C:36]2[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=2[NH:34][C:33]1=[O:41]>>[CH3:30][O:29][N:27]([CH3:28])[C:25]([C:10]1[C:11]2[C:16](=[O:17])[N:15]([CH3:18])[C:14](=[O:19])[N:13]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:12]=2[S:24][C:9]=1[CH2:8][N:34]1[C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=2[O:32][C:33]1=[O:41])=[O:26]

Participants

3

Reactant 2

HCID 60432(3H)-BenzoxazoloneHCID 10184774HCID 10184774, compound

Product 1

HCID 10162370HCID 10162370, compound

Procedure

The subtitle compound was synthesised by the method of example 1 c) using the product of example 1 part b) and benzoxazolone. The product was isolated by SiO2 chromatography eluting with ethyl acetate/i-hexane (3:2), followed by recrystallisation with diethyl ether to so give the sub-title compound.

Workup

  1. customThe subtitle compound was synthesised by the method of example 1 c)
  2. customThe product was isolated by SiO2 chromatography
  3. washeluting with ethyl acetate/i-hexane (3:2)
  4. customfollowed by recrystallisation with diethyl ether

Sources & evidence

ORD record
ord-cca8d465f3e3457d942b1588c48ccee9
Source dataset
uspto-grants-2008_04
Patent number
US07361660B2

Reaction notes

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