methyl 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylate → 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid

HRID 900795Notes

Reaction equation

HRID 900795 reaction equation
[O:1]=[C:2]1[NH:17][C:5]2=[CH:6][C:7]3[CH:8]=[C:9]([C:13]([O:15]C)=[O:14])[NH:10][C:11]=3[CH:12]=[C:4]2[O:3]1>O>[O:1]=[C:2]1[NH:17][C:5]2=[CH:6][C:7]3[CH:8]=[C:9]([C:13]([OH:15])=[O:14])[NH:10][C:11]=3[CH:12]=[C:4]2[O:3]1

Participants

3

Reactant 1

HCID 16110270methyl 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylate

Product 1

HCID 223501592-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The title compound is prepared from methyl 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylate according to the method described in Example 1/b. Mp.: 288-290° C. (water).

Sources & evidence

ORD record
ord-5ed4f1f713a74e7d9f6e81fc1bf50f20
Source dataset
uspto-grants-2008_04
Patent number
US07361670B2

Reaction notes

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