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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 900905Generated: October 30, 2026

4-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide → HCID 11997325, compound

https://huagongshe.com/reaction/900905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 67218757—
Reactant5-(3-Methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acidHCID 86607114—
ProductHCID 11997325HCID 11997325—

Reaction Steps

The title compound was prepared from 5-(3-methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.8) and 4-amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide (example B.2) according to general procedure II. Yellow solid. MS (ISP) 654.2 [(M−H)−]; mp 207° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07361659B2
Source datasetuspto-grants-2008_04
ORD IDord-9f5ddfe791644690b2bd3c3596c837dc
Source noteuspto-grants-2008_04