HRID900906

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67218757

未命名化合物

结构：O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)c(OCC(F)(F)F)c3)nc12

HCID86607115

未命名化合物

PRODUCTS

生成物

结构：CC(C)(CO)NS(=O)(=O)c1cc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)c(OCC(F)(F)F)c4)nc23)c(Cl)s1

HCID11997326

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-[3-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.10) and 4-amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide (example B.2) according to general procedure II.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cac78d689dfd41e29db2963afa4a2fa8
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07361659B2
来源说明: uspto-grants-2008_04

反应 SMILES

[F:1][C:2]([F:32])([F:31])[CH2:3][O:4][C:5]1[CH:6]=[C:7]([C:15]2[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[N:18]3[N:25]=[CH:26][C:27]([C:28](O)=[O:29])=[C:17]3[N:16]=2)[CH:8]=[CH:9][C:10]=1[C:11]([F:14])([F:13])[F:12].[OH:33][CH2:34][C:35]([NH:38][S:39]([C:42]1[S:43][C:44]([Cl:48])=[C:45]([NH2:47])[CH:46]=1)(=[O:41])=[O:40])([CH3:37])[CH3:36]>>[Cl:48][C:44]1[S:43][C:42]([S:39](=[O:41])(=[O:40])[NH:38][C:35]([CH3:37])([CH3:36])[CH2:34][OH:33])=[CH:46][C:45]=1[NH:47][C:28]([C:27]1[CH:26]=[N:25][N:18]2[C:19]([C:21]([F:22])([F:24])[F:23])=[CH:20][C:15]([C:7]3[CH:8]=[CH:9][C:10]([C:11]([F:14])([F:13])[F:12])=[C:5]([O:4][CH2:3][C:2]([F:32])([F:31])[F:1])[CH:6]=3)=[N:16][C:17]=12)=[O:29]