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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 900919Generated: November 1, 2026

7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid → HCID 86607120, compound

https://huagongshe.com/reaction/900919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acidHCID 66650268—
Reactant4-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amideHCID 67218795—
ProductHCID 86607120HCID 86607120—

Reaction Steps

The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 4-amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide (example B.7) according to general procedure II. Light yellow solid. MS (ISP) 638.0 [(M−H)−]; mp 237° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07361659B2
Source datasetuspto-grants-2008_04
ORD IDord-7a8f1fa955c545b795321d25d98b0a31
Source noteuspto-grants-2008_04