HRID900937

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)CCN(CCN(C)C)S(=O)(=O)c1cc([N+](=O)[O-])c(Cl)s1

HCID67218946

未命名化合物

结构：O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12

HCID86607112

未命名化合物

PRODUCTS

生成物

结构：CN(C)CCNS(=O)(=O)c1cc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)c(Cl)s1

HCID11997756

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 4-amino-5-chloro-thiophene-2-sulfonic acid (2-dimethylamino-ethyl)-amide (example B.14) according to general procedure II.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1c7fbd5006a24b788f083eeb4249686c
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07361659B2
来源说明: uspto-grants-2008_04

反应 SMILES

[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[CH3:27][N:28]([CH3:49])[CH2:29][CH2:30][N:31](CCN(C)C)[S:32]([C:35]1[S:36][C:37]([Cl:43])=[C:38]([N+:40]([O-])=O)[CH:39]=1)(=[O:34])=[O:33]>>[Cl:43][C:37]1[S:36][C:35]([S:32](=[O:34])(=[O:33])[NH:31][CH2:30][CH2:29][N:28]([CH3:49])[CH3:27])=[CH:39][C:38]=1[NH:40][C:12]([C:11]1[CH:10]=[N:9][N:8]2[C:3]([C:2]([F:1])([F:25])[F:26])=[CH:4][C:5]([C:15]3[CH:20]=[CH:19][C:18]([C:21]([F:22])([F:24])[F:23])=[CH:17][CH:16]=3)=[N:6][C:7]=12)=[O:13]