2-Amino-4-methyl-thiazole-5-sulfonic acid (2-dimethylamino-ethyl)-amide → HCID 11996405, compound

HRID 900940Notes

Reaction equation

HRID 900940 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12]([OH:14])=O)=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[CH3:27][N:28]([CH3:42])[CH2:29][CH2:30][NH:31][S:32]([C:35]1[S:39][C:38]([NH2:40])=[N:37][C:36]=1[CH3:41])(=[O:34])=[O:33]>>[CH3:27][N:28]([CH3:42])[CH2:29][CH2:30][NH:31][S:32]([C:35]1[S:39][C:38]([NH:40][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([C:2]([F:26])([F:25])[F:1])=[CH:4][C:5]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:22])([F:24])[F:23])=[CH:17][CH:16]=4)=[N:6][C:7]=23)=[O:14])=[N:37][C:36]=1[CH3:41])(=[O:34])=[O:33]

Participants

3

Reactant 2

HCID 639465802-Amino-4-methyl-thiazole-5-sulfonic acid (2-dimethylamino-ethyl)-amideHCID 866071127-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11996405HCID 11996405, compound

Procedure

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 2-amino-4-methyl-thiazole-5-sulfonic acid (2-dimethylamino-ethyl)-amide (example B.15) according to general procedure II.

Sources & evidence

ORD record
ord-b0a6b44adbe8435c9ddd27170c470062
Source dataset
uspto-grants-2008_04
Patent number
US07361659B2

Reaction notes

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