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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 900941Generated: October 30, 2026

2-Amino-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide → HCID 11996555, compound

https://huagongshe.com/reaction/900941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 86607105—
Reactant7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acidHCID 86607112—
ProductHCID 11996555HCID 11996555—

Reaction Steps

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C. 1) and 2-amino-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide (example B.13) according to general procedure II. Yellow solid. MS (ISP) 607.0 [(M−H)−]; mp 292° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07361659B2
Source datasetuspto-grants-2008_04
ORD IDord-7ed921de6bc3425d908cd192421b42d7
Source noteuspto-grants-2008_04