HRID901011

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID677042

[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid

C12H9ClN2O3S

HCID14674154

Pyridine, 2-(4-piperidinyloxy)-, hydrochloride (1:2)

C10H16Cl2N2O

PRODUCTS

生成物

结构：O=C(Nc1nc(CC(=O)N2CCC(Oc3ccccn3)CC2)cs1)c1ccc(Cl)cc1

HCID59698874

未命名化合物

PROCEDURE

实验过程

In analogy to example 1.3, [2-(4-chloro-benzoylamino)-thiazol-4-yl]-acetic acid (example 1.2) was coupled with 2-(piperidin-4-yloxy)-pyridine dihydrochloride (CAS 313490-36-7) to give 4-chloro-N-(4-{2-oxo-2-[4-(pyridin-2-yloxy)-piperidin-1-yl]-ethyl}-thiazol-2-yl)-benzamide, using general procedure C. White amorphous solid. MS 457.6 ([M+H]+)