HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl piperazine-1-acetate → (4-{2-[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetyl}-piperazin-1-yl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl piperazine-1-acetate | HCID 207112 | — |
| Reactant | [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid | HCID 677042 | — |
| Product | (4-{2-[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetyl}-piperazin-1-yl)-acetic acid ethyl ester | HCID 59698848 | — |
Reaction Steps
22.1 Using general procedure A, [2-(4-chloro-benzoylamino)-thiazol-4-yl]-acetic acid (example 1.2) was coupled with 1-(ethoxycarbonylmethyl)-piperazine to give (4-{2-[2-(4-chloro-benzoylamino)-thiazol-4-yl]-acetyl}-piperazin-1-yl)-acetic acid ethyl ester. Off-white solid. MS 473.1 ([M+Na]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07361672B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-3f8cf90279bf45d38f82cf0154a51caa |
| Source note | uspto-grants-2008_04 |