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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 901199Generated: October 26, 2026

(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylic acid → ((1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone

https://huagongshe.com/reaction/901199

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylic acidHCID 11402372—
Reactant5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,6-naphthyridineHCID 11481097—
Product((1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanoneHCID 59700298—

Reaction Steps

reacting (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid with 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine to form 6-{[(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-en-1-yl]carbonyl}-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07361765B2
Source datasetuspto-grants-2008_04
ORD IDord-acfb2ffc2e5349969cd2c2661f7d7e3e
Source noteuspto-grants-2008_04