Sodium Hydroxide → (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylic acid

HRID 901203Notes

Reaction equation

HRID 901203 reaction equation
[CH3:1][C:2]1[N:3]([C@H:8]2[CH2:12][C@@:11]([CH:17]([CH3:19])[CH3:18])([C:13]([O:15]C)=[O:14])[CH:10]=[CH:9]2)[C:4]([CH3:7])=[CH:5][CH:6]=1.[OH-].[Na+]>CO>[CH3:7][C:4]1[N:3]([C@H:8]2[CH2:12][C@@:11]([CH:17]([CH3:19])[CH3:18])([C:13]([OH:15])=[O:14])[CH:10]=[CH:9]2)[C:2]([CH3:1])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 59700295(1S,4S)-Methyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylate

Product 1

HCID 11402372(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-enecarboxylic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

reacting said methyl (1S,4S)-4-(2,5dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylate with NaOH and MeOH to form (1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid.

Sources & evidence

ORD record
ord-925658d2722a45869328d51abfec6cab
Source dataset
uspto-grants-2008_04
Patent number
US07361765B2

Reaction notes

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