反应详情

Under an atmosphere of argon, 1-(2,2-diphenylvinyl)-3,5-dibromo-benzene (8.3 g, 20 mmole), 1-naphthaleneboronic acid (3.4 g, 20 mmole) and tetrakis(triphenylphosphine)palladium(0) (0.46 g, 0.4 mmole, 2% Pd) were dissolved into toluene (50 ml). To the obtained solution, a 2 M aqueous solution of sodium carbonate (30 ml, 60 mmole, 3 eq) was added. The resultant solution was heated under refluxing for 10 hours and left standing for one night. The formed organic layer was separated, washed with a saturated aqueous solution of sodium chloride (50 ml) and dried with anhydrous magnesium sulfate. Then, the solvent was removed by distillation and a yellow oil was obtained. The obtained oil was purified by the column chromatography (silica gel/hexane, hexane+3% dichloro-methane and hexane+10% dichloromethane, successively) and a white glass solid (5.5 g, 60%) was obtained.

1. temperatureunder refluxing for 10 hours
2. waitleft
3. waitstanding for one night
4. customThe formed organic layer was separated
5. washwashed with a saturated aqueous solution of sodium chloride (50 ml)
6. dry with materialdried with anhydrous magnesium sulfate
7. customThen, the solvent was removed by distillation
8. customa yellow oil was obtained
9. customThe obtained oil was purified by the column chromatography (silica gel/hexane, hexane+3% dichloro-methane and hexane+10% dichloromethane