HCID 10201122, compound → HCID 178468198, compound

Participants

Reaction Steps

(S)-3-[4-{3-(7-Fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-4-yl)propylamino}phenyl]-2-ethoxypropanoic acid (300 mg, 1 eq, 0.74 mmol) obtained in example 46, and L-arginine (130 mg, 1 eq, 0.74 mmol) were taken in dry methanol (4 ml), and stirred at RT for 2-3 h. The solvent was removed on rotavapour followed by benzene azeotrope. The residue was dried under high vacuum pump to yield the title compound as a free following solid (yield 100%).

Provenance & Evidence