Benzonitrile → HCID 178512042, compound

HRID 901908Notes

Reaction equation

[C:1](#[N:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:9][C:10]1[CH:16]=[CH:15][C:13]([NH2:14])=[CH:12][CH:11]=1>>[F:9][C:10]1[CH:16]=[CH:15][C:13]([NH:14][C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[NH:8])=[CH:12][CH:11]=1

Participants

Reactant 2

HCID 7505Benzonitrile

HCID 97314-Fluoroaniline

Product 1

HCID 178512042HCID 178512042, compoundYield 85.1%

Procedure

The title compound was prepared from benzonitrile (13.9 g, 135 mmol) and 4-fluoroaniline (15 g, 135 mmol) by following the procedure described in preparation 10 (24.6 g, yield 85.1%, purity 99.7% by HPLC). MS m/z:215.2 (M+).

Workup

customdescribed in preparation 10 (24.6 g, yield 85.1%, purity 99.7% by HPLC)

Sources & evidence

ORD record: ord-1cced806c2814933b20034d0db8565e3
Source dataset: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07365069B2

Reaction notes

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