3,4-Dimethylaniline → HCID 178426509, compound

Participants

Reaction Steps

The title compound was prepared from 2-cyanopyridine (8.6 g, 83 mmol) and 3,4-dimethylaniline (10 g, 83 mmol) by following the procedure described in preparation 10 (13.2 g, yield 71.2%, mp 105-107° C., purity 99.9% by HPLC). 1H-NMR (CDCl3): δ 2.24-2.25 (d, 6H), 5.75-6 (bs, 2H, D2O exchangeable), 6.75-6.81 (m, 2H), 7.11-7.13 (d, 1H), 7.36-7.39 (m, 1H), 7.78-7.82 (m, 1H) 8.39-8.41 (d, 1H), 8.55-8.57 (m, 1H). IR (KBr) cm−1: 3445, 3303, 1645, 1625. MS m/z:227 (M+).

Provenance & Evidence