HCID 15637840, compound → (2R,3R)-3-Amino-1,2,3,4-tetrahydronaphthalen-2-ol

Participants

Reaction Steps

A stirring mixture of trans 3-azido-2-hydroxy-1,2,3,4-tetrahydronaphthalene (2.5 g, about 75% pure) dissolved in methanol (132 mL) and 10% palladium on carbon (250 mg) was hydrogenated for 2 h under a hydrogen balloon at room temperature. The reaction mixture was filtered through Celite®, rinsing with methanol, and then evaporated under vacuum to provide the title compound (2.2 g, 72% pure).

Provenance & Evidence