4-Benzylpyridine → HCID 86600924, compound

Participants

Reaction Steps

A solution of 4-benzyl pyridine (0.6 g, 3.5 mmol) in methylene chloride (5 ml) is cooled with ice bath. Freshly prepared O-(2,4,6-trimethyl-benzenesulfonyl)hydroxylamine (0.92 g, 4.2 mmol) in methylene chloride (5 ml) is added dropwise with stirring. The ice bath is removed and the mixture stirred for 1 hour, then concentrated in vacuo. The residue is dissolved in methylene chloride and precipitated with hexanes. The hexane layer is decanted. Concentration provides 1.0 g (62%) of the title compound as a viscous oil.

Provenance & Evidence