HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902020Generated: October 28, 2026
Dimethylformamide → HCID 59700613, compound
https://huagongshe.com/reaction/902020
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 135983747 | HCID 135983747 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59700613 | HCID 59700613 | — |
Reaction Steps
4-(2-Pyridin-2-yl-pyrazolo[1,5-a]pyridin-3-yl)-quinolin-7-ol in a solution of DMF and MeOH is treated with 1-bromo-3-chloropropane (3 equiv) and cesium carbonate (2 equiv). The reaction is heated to 60° C. and stirred overnight. The reaction is then purified on silica gel column (see Prep. 77) chromatography to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07365066B2 |
|---|
| Source dataset | uspto-grants-2008_04 |
|---|
| ORD ID | ord-4dbb74bec96844eeae798d9b6b163225 |
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| Source note | uspto-grants-2008_04 |
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