Ethanol → HCID 10404576, compound

Participants

Reaction Conditions

Reaction Steps

Add sodium hydride (20.7 mg, 0.52 mmol) to a solution of 2-(6-chloro-pyridin-2-yl)-3-(4-fluoro-phenyl)-pyrazolo[1,5-a]pyridine (33.5 mg, 0.10 mmol) in ethanol (2.5 mL) at 0° C. Stir the reaction mixture at 0° C. for 30 minutes and at 80° C. for 48 hours. Cool the reaction mixture to room temperature and concentrate in vacuo Using the same procedure as above afforded the title compound 31 mg (93%) as an off-white solid.

Provenance & Evidence