反应详情

A stirred solution of of thionyl chloride in toluene is cooled to 0° C., and a catalytic amount of pyridine is added. A solution of 1,2-di(4-chlorophenyl)ethan-1-ol in toluene is then added drop wise. Upon completion addition of addition, the reaction mixture is allowed to warm to ambient temperature where it stirs for about 30 minutes. The reaction mixture is washed with water, dried with sodium sulfate, filtered, and concentrated under reduced pressure, yielding the subject compound.

1. additionUpon completion addition of addition
2. washThe reaction mixture is washed with water
3. dry with materialdried with sodium sulfate
4. filtrationfiltered
5. concentrationconcentrated under reduced pressure
6. customyielding the subject compound