2-Thiophenecarboxaldehyde → HCID 57434517, compound

HRID 902123Notes

Reaction equation

HRID 902123 reaction equation
[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2C=C[C:17](C)=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.[S:28]1C=CC=C1C=O>>[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[S:28][CH:17]=[CH:16][CH:15]=2)[O:6][C:7]=1[CH3:8]

Participants

4

Reactant 3

HCID 73642-ThiophenecarboxaldehydeHCID 64096332,3-Butanedione monoximeHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

Product 1

HCID 57434517HCID 57434517, compound

Procedure

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and thiophene-2-carbaldehyde gave 4-iodomethyl-5-methyl-2-thiophen-2-yloxazole.

Sources & evidence

ORD record
ord-da634cc4755c49a98e911caf3474f3bd
Source dataset
uspto-grants-2008_04
Patent number
US07365084B2

Reaction notes

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