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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902127Generated: October 30, 2026

3,4-Dimethylbenzaldehyde → 2-(3,4-Dimethylphenyl)-4-iodomethyl-5-isopropyloxazole

https://huagongshe.com/reaction/902127

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethylbenzaldehydeHCID 22278—
Reactant4-Methylpentane-2,3-dione 2-oximeHCID 57357475—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product2-(3,4-Dimethylphenyl)-4-iodomethyl-5-isopropyloxazoleHCID 59701372—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, 4-methylpentane-2,3-dione-2-oxime and 3,4-dimethylbenzaldehyde gave 2-(3,4-dimethylphenyl)-4-iodomethyl-5-isopropyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365084B2
Source datasetuspto-grants-2008_04
ORD IDord-784ca304f89f4d15846099208551a005
Source noteuspto-grants-2008_04