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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902147Generated: October 29, 2026

4-(Benzyloxy)piperidine → 6-(4-Benzyloxypiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indole-2-one

https://huagongshe.com/reaction/902147

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Benzyloxy)piperidineHCID 3157460—
Reactant2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acidHCID 22350159—
SolventDiethyl EtherHCID 3283—
Product6-(4-Benzyloxypiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indole-2-oneHCID 22350201—

Reaction Steps

The title compound is prepared from 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid and 4-benzyloxypiperidine [Tetrahedron 54, 13981, (1998)] according to the method described in Example 1/c. Mp.: 258-261° C. (diethyl ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365083B2
Source datasetuspto-grants-2008_04
ORD IDord-3b70c3c4b0d84e26b65797e5222c1b11
Source noteuspto-grants-2008_04