HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Fluoro-benzyl)-piperidine → 6-(4-(4-Fluorobenzyl)piperidin-1-carbonyl]-1,5-dihydro-oxazolo[4,5-f]indole-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Fluoro-benzyl)-piperidine | HCID 3699841 | — |
| Reactant | 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid | HCID 22350159 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 6-(4-(4-Fluorobenzyl)piperidin-1-carbonyl]-1,5-dihydro-oxazolo[4,5-f]indole-2-one | HCID 22350190 | — |
Reaction Steps
The title compound is prepared from 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid and 4-(4-fluorobenzyl)piperidine [J. Med. Chem., 35, 4903, (1992)] according to the method described in Example 1/c. Mp.: 244-247° C. (diethyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365083B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-4fbceb1900124599a2e81c03f1e14b6d |
| Source note | uspto-grants-2008_04 |