Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902161Generated: October 26, 2026

4-(4-Fluoro-benzyl)-piperidine → 2-[4-(4-Fluorobenzyl)piperidin-1-carbonyl]-1,5-dihydro-8-oxa-1,5-diaza-cyclopenta[b]naphthalene-6-one

https://huagongshe.com/reaction/902161

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluoro-benzyl)-piperidineHCID 3699841—
ReactantHCID 22350172HCID 22350172—
SolventDiethyl EtherHCID 3283—
Product2-[4-(4-Fluorobenzyl)piperidin-1-carbonyl]-1,5-dihydro-8-oxa-1,5-diaza-cyclopenta[b]naphthalene-6-oneHCID 22350194—

Reaction Steps

The title compound is prepared from 6-oxo-1,5,6,7-tetrahydro-8-oxa-1,5-diaza-cyclopenta[b]naphthalene-2-carboxylic acid and 4-(4-fluorobenzyl)piperidine according to the method described in Example 1/c. Mp.: 219-226° C. (diethyl ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365083B2
Source datasetuspto-grants-2008_04
ORD IDord-a8b58e8b73964aa6aae6b8147db0974e
Source noteuspto-grants-2008_04