HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86609137, compound → HCID 86609139, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86609137 | HCID 86609137 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86609139 | HCID 86609139 | 98.1% |
Reaction Steps
Treatment of ((2R)-7-chloro-8-(2-chlorophenyl)-2H-chromen-2-yl)methyl 4-methylbenzenesulfonate (2.13 g, 4.62 mmol) in ethanol (100 mL) and ethyl acetate (15 mL) with platinum (IV) oxide (84% Pt, 0.50 g) according to the procedure described for Example 69, Step 8 provided 2.10 g (96%) of ((2R)-7-chloro-8-(2-chlorophenyl)chroman-2-yl)methyl 4-methylbenzenesulfonate as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-2e79244a17cc4be8941edaab766504ea |
| Source note | uspto-grants-2008_04 |