HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-chloro-1-methylbenzene → HCID 69116784, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-chloro-1-methylbenzene | HCID 609898 | — |
| Reactant | (2-Fluoro-6-methoxyphenyl)boronic acid | HCID 3294524 | — |
| Reactant | Water 1,2-dimethoxyethane | HCID 18180031 | — |
| Product | HCID 69116784 | HCID 69116784 | — |
Reaction Steps
Treatment of 2-bromo-4-chlorotoluene (20 mL, 0.15 mol) with 2-fluoro-6-methoxybenzene boronic acid (10.0 g, 58.8 mmol) in DME-water (5:1, 300 mL) according to the procedure described for Example 69, Step 1 provided 21.0 g of 4-chloro-2′-fluoro-6′-methoxy-2-methylbiphenyl as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-329fc850df854f9e970cff944eb64225 |
| Source note | uspto-grants-2008_04 |