HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mesitylene → HCID 69117472, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mesitylene | HCID 7947 | — |
| Reactant | 2'-Allyloxy-4-chloro-6'-fluoro-2-methylbiphenyl | HCID 69116906 | — |
| Product | HCID 69117472 | HCID 69117472 | 95% |
Reaction Steps
A solution of 2′-allyloxy-4-chloro-6′-fluoro-2-methylbiphenyl (2.1 g, 7.6 mmol) in mesitylene (70 mL) was refluxed for 24 h. The solvent was removed under reduced pressure. Purification by ISCO using a solvent gradient of 0 to 20% ethyl acetate in hexanes provided 2.0 g (95%) of 3-allyl-4′-chloro-6-fluoro-2′-methylbiphenyl-2-ol as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-6b4638b859ad489098b801cb2b86c494 |
| Source note | uspto-grants-2008_04 |