HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → HCID 86609148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 86609147 | HCID 86609147 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86609148 | HCID 86609148 | 83% |
Reaction Steps
Treatment of ((2R)-8-(4-chloro-2-methylphenyl)-7-fluorochroman-2-yl)methyl 4-methylbenzenesulfonate (0.5 g, 1.09 mmol) with sodium azide (0.43 g, 6.54 mmol) in DMSO (15 mL) according to the procedure described for Example 69, Step 9 provided 0.30 g (83%) of (2R)-2-(azidomethyl)-8-(4-chloro-2-methylphenyl)-7-fluorochroman as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-3ffce8444efe4422b98850c7c1663bd8 |
| Source note | uspto-grants-2008_04 |