HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86609149, compound → HCID 86609151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86609149 | HCID 86609149 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86609151 | HCID 86609151 | 100% |
Reaction Steps
Treatment of ((2R)-8-(2,4-dichlorophenyl)-7-fluoro-2H-chromen-2-yl)methyl 4-methylbenzenesulfonate (0.35 g, 0.73 mmol) with platinum (IV) oxide (84% Pt, 0.14 g) in ethanol (20 mL) and ethyl acetate (5 mL) according to the procedure described for Example 69, Step 8 provided 0.35 g (100%) of ((2R)-8-(2.4-dichlorophenyl)-7-fluorochroman-2-yl)methyl 4-methylbenzenesulfonate as a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-7dc70d0756484c5b859bc8c80866d6da |
| Source note | uspto-grants-2008_04 |