HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Valienamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 444254 | HCID 444254 | — |
| Product | Valienamine | HCID 193758 | 77.4% |
Reaction Steps
10 g of pure acarbose were place into 10% TFA solution at 5% final concentration. While putting pressure using an autoclave, at a reaction temperature of 121° C., it was reacted for 30 minutes to 1 hour, followed by removal of TFA and water. Then, by using ion-exchange resins for purification, 2.1 g of valienamine were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365192B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-be48d6b7d69a44728d8f6a2b53abaaa5 |
| Source note | uspto-grants-2008_04 |