反应详情

Tricyclo[8.2.1.03,8]trideca-3(8),4,6-trien-13-one (130 mg, 0.70 mmol) and benzenesulfonamide (110 mg, 0.70 mmol) were mixed in toluene (6 mL). Amberlyst-15 ion exchange resin (35 mg) was added, and the mixture was heated at reflux under Dean Stark conditions for 36 h. The mixture was concentrated and the crude sulfonylimine was used directly in the next step.

1. temperaturethe mixture was heated
2. temperatureat reflux under Dean Stark conditions for 36 h
3. concentrationThe mixture was concentrated