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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9025Generated: October 26, 2026

5-Chloroindole → 5-chloro-3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-1H-indole

https://huagongshe.com/reaction/9025

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-ChloroindoleHCID 87110—
Reactant1-(2-Methoxy-benzylidene)pyrrolidinium chlorideHCID 17912253—
Product5-chloro-3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-1H-indoleHCID 10268860—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and 1-(2-methoxy-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 24.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-caea7a624f0243c3b2e28a344715d0ec
Source noteuspto-grants-2006_08