Hydrochloric Acid → HCID 11953114, compound

Participants

Reaction Steps

A mixture of 2.00 g (6.26 mmol) of 2,2-bis(4-hydroxyphenyl)adamantane, 2.00 g (12.7 mmol) of 5-fluoro-2-nitrophenol, 1.70 g (12.3 mmol) of anhydrous K2CO3, and 50 mL of dry DMF was reflux for 12 h under nitrogen. The mixture was allowed to cool and subsequently poured into 500 mL of distilled water. The resulting solution was acidied by concentrated hydrogen chloride to pH=3.5˜4.0. The precipitated product was collected, washed thoroughly with water until neutral, and then dried to give 2.75 g (73.9%) of 2,2-bis(4-(3-hydroxy-4-nitrophenoxy)phenyl)adamantane. mp 248˜250° C.; Elemental Anal. Calcd. for C34H30N2O8: C, 68.69; H, 5.05; N, 4.71. Found: C, 68.58; H, 5.10; N, 4.68. MS (EI) m/z 594 (M+, 100); IR (KBr): 3402, 2896, 2868, 1576, 1322 cm−1.

Provenance & Evidence