HRID902728

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(CNCc1cccc(C(F)(F)F)c1Cl)c1ccccc1Cl

HCID69252183

未命名化合物

结构：COC(=O)C=C1C=CC=C(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(C)c2ccccc2Cl)C1

HCID69253617

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C=C1C=CC=C(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(C)c2cccc(Cl)c2)C1

HCID69254719

未命名化合物

收率 49%

PROCEDURE

实验过程

The titled compound was prepared from N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propylamine in 49% yield in the same manner as the preparation of N-(2-[2-Chlorophenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine in Example 184f. MS (ESI) 568 (MH+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e9721861d6104e45bfa2f66188e6c69f
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07365085B2
来源说明: uspto-grants-2008_04

反应 SMILES

[Cl:1]C1C(C(F)(F)F)=CC=CC=1CNCC(C1C=CC=CC=1Cl)C.Cl[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[CH:31]([CH3:61])[CH2:32][N:33]([CH2:46][CH2:47][CH2:48][O:49][C:50]1[CH2:51][C:52](=[CH:56][C:57]([O:59][CH3:60])=[O:58])[CH:53]=[CH:54][CH:55]=1)[CH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[C:37]([C:41]([F:44])([F:43])[F:42])[C:36]=1[Cl:45]>>[Cl:1][C:30]1[CH:25]=[C:26]([CH:31]([CH3:61])[CH2:32][N:33]([CH2:46][CH2:47][CH2:48][O:49][C:50]2[CH2:51][C:52](=[CH:56][C:57]([O:59][CH3:60])=[O:58])[CH:53]=[CH:54][CH:55]=2)[CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[C:37]([C:41]([F:44])([F:43])[F:42])[C:36]=2[Cl:45])[CH:27]=[CH:28][CH:29]=1