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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902731Generated: October 31, 2026

DL-2-(4-chlorophenyl)propanoic acid → N-(2-chloro-3-trifluoromethylbenzyl)-2-(4-chlorophenyl)propionamide

https://huagongshe.com/reaction/902731

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDL-2-(4-chlorophenyl)propanoic acidHCID 102525—
ReactantN-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamideHCID 69254638—
ProductN-(2-chloro-3-trifluoromethylbenzyl)-2-(4-chlorophenyl)propionamideHCID 6925346632%

Reaction Steps

The titled compound was prepared from 2-(4-Chlorophenyl)propionic acid in 32% yield in the same manner as the preparation of N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamide in Example 184b. MS (ESI) 376 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365085B2
Source datasetuspto-grants-2008_04
ORD IDord-875beb105839407a889e58136f42c7fd
Source noteuspto-grants-2008_04